TY - JOUR
AU - Edward Schrom
AU - Stuart Feldman
AU - Carl T. Bergstrom
AU - Stephanie Forrest
AU - Andrea L. Graham
AU - Simon A. Levin
AU - Ann Kinzig
AU - Carlos Castillo-Chavez
AU - Adam Doupé
AU - James P. Collins
AU - Rob J. de Boer
AU - Mohit Tiwari
AU - Roya Ensafi
AU - Charles Perrings
AU - J. Alex Halderman
AU - Silvie Huijben
AU - Bryan T. Grenfell
AU - Melanie Moses
AU - Carlo Maley
AU - Jennifer Rexford
AU - Alan S. Perelson
AU - Joshua Plotkin
AB - we present a conceptual framework for structured comparisons across the fields of biological immunity and cybersecurity, by framing the context of defense, considering different (combinations of) defensive strategies, and evaluating defensive performance. Throughout this paper, we pose open questions for further exploration. We hope to spark the interdisciplinary discovery of general principles of optimal defense, which can be understood and applied in biological immunity, cybersecurity, and other defensive realms.
BT - Elsevier BV
DA - 2023-08
DO - 10.1016/j.mbs.2023.109024
N1 - Across evolved biological immunity and engineered cybersecurity, we find meaningful parallels in how the defensive contexts are framed, strategies chosen, and performance evaluated. Especially as technological advances allow these two defensive systems to resemble one another more closely, we believe that carefully drawn analogies between these systems can reveal general principles of defensive design to protect against unpredictable attacks. Lists of proposed principles already exist in some fields , but their generality across systems has not been examined in depth, either theoretically or practically. We hope the open questions articulated above will spark collaborative study, whether by sharing data and analytical techniques or constructing theoretical models. Finally, as general defensive design principles emerge, we hope to see them vetted and successfully deployed in other realms, such as national defense against domestic and international terrorism, and public health defense against zooneses and epidemics.
N2 - we present a conceptual framework for structured comparisons across the fields of biological immunity and cybersecurity, by framing the context of defense, considering different (combinations of) defensive strategies, and evaluating defensive performance. Throughout this paper, we pose open questions for further exploration. We hope to spark the interdisciplinary discovery of general principles of optimal defense, which can be understood and applied in biological immunity, cybersecurity, and other defensive realms.
PY - 2023
T2 - Elsevier BV
TI - Challenges in cybersecurity: Lessons from biological defense systems
UR - https://www.sciencedirect.com/science/article/pii/S0025556423000652
SN - 0025-5564
ER -